Marble Anion Gap

Abnormal anion gap is a relatively common occurrence among hospitalized patients with increased anion gap being far more common than reduced anion gap.

Marble anion gap.

Metabolic acidosis with high anion gap without increased serum chloride severe alkalemia albumin become negatively charged references. A retrospective study of 6868 sets of serum electrolytes among hospitalized patients 3 for example revealed incidences of increased and reduced anion gap to be 37 6 and 2 9 respectively. Na cl hc03 anion gap or na k cl hco3 anion gap. Anion gap decreases 2 5 meq per 1 g dl albumin drop.

Recent evidence 3 indicates that diabetic ketoacido sis should no longer be viewed simply as wide anion gap metabolic acidosis. Thus the finding of a normal anion gap per se may not exclude the presence of diabetic ketoacidosis. I know there are a couple of calculations and wanted to know is one calculation better than the other. Ever wondered what on earth the anion gap was all about.

But when you ve got yourself a metabolic acidosis this is a good place to start. In contrast the differential diagnosis of metabolic acidosis with a normal anion gap is essentially limited to two conditions diarrhea and renal tubular acidosis. Killu and sarani 2016 fundamental critical care support p.